Strategies for the long-term treatment of schizophrenia: real-world lessons from the CATIE trial.

摘要: Patients with schizophrenia have a chronic illness necessitating biopsychosocial model of care that addresses the multiple dimensions disease, including coordinated primary care. Current research, lessons learned from Clinical Antipsychotic Trials Intervention Effectiveness (CATIE) study, shows in addition to education, adherence, and minimizing adverse effects psychopharmacologic agents, multimodal long-term treatment strategies are needed address medical comorbidities, substance abuse, both cognitive social deficits. Health professionals responsibility monitor help prevent outcomes related antipsychotics, light evidence patients at risk for metabolic disorders undertreated highly prevalent cardiovascular factors. These problems particularly challenging this population due chronicity symptoms, limitations, financial challenges, compliance issues recommended medication therapeutic lifestyle changes. Mental health providers United States now studying models support integration psychiatric nonpsychiatric complexity