Anticipating Cutoff Diameters in Deterministic Lateral Displacement (DLD) Microfluidic Devices for an Optimized Particle Separation.

摘要: Deterministic lateral displacement (DLD) devices enable to separate nanometer micrometer-sized particles around a cutoff diameter, during their transport through microfluidic channel with slanted rows of pillars. In order design appropriate DLD geometries for specific separation sizes, robust models are required anticipate the value diameter. So far, proposed result in single diameter given geometry. This paper shows that actually varies along channel, especially narrow pillar arrays. Experimental and numerical results reveal variation is induced by boundary effects at side walls, called wall effect. The effect generates unexpected particle trajectories may compromise efficiency. when designing devices, predictive model this work has been validated experimentally. addition usual geometrical parameters, new parameter, number pillars cross dimension, considered investigate its influence on trajectories.