A pore mutation in a novel KQT-like potassium channel gene in an idiopathic epilepsy family.

作者: Carole Charlier , Nanda A. Singh , Stephen G. Ryan , Tracey B. Lewis , Bonnie E. Reus

DOI: 10.1038/NG0198-53

关键词:

摘要: … -Iike potassium channel gene in an idiopathic epilepsy family … % of these are idiopathic generalized epilepsies (IGEs; ref. 1)… This gene, a voltage-gated potassium channel, based on …

参考文章(25)
M Boehnke, K Lange, D R Cox, Statistical methods for multipoint radiation hybrid mapping. American Journal of Human Genetics. ,vol. 49, pp. 1174- 1188 ,(1991)
Stephen G. Ryan, Ken Ward, Tracey B. Lewis, Robin J. Leach, Peter O'Connell, Genetic heterogeneity in benign familial neonatal convulsions: identification of a new locus on chromosome 8q. American Journal of Human Genetics. ,vol. 53, pp. 670- 675 ,(1993)
Ortrud Steinlein, Volker Schuster, Christine Fischer, Martin H�ussier, Benign familial neonatal convulsions: confirmation of genetic heterogeneity and further evidence for a second locus on chromosome 8q. Human Genetics. ,vol. 95, pp. 411- 415 ,(1995) , 10.1007/BF00208966
Colette Dib, Sabine Fauré, Cécile Fizames, Delphine Samson, Nathalie Drouot, Alain Vignal, Philippe Millasseau, Sophie Marc, Jamile Kazan, Eric Seboun, Mark Lathrop, Gabor Gyapay, Jean Morissette, Jean Weissenbach, A comprehensive genetic map of the human genome based on 5,264 microsatellites Nature. ,vol. 380, pp. 152- 154 ,(1996) , 10.1038/380152A0
H.L. Drwinga, L.H. Toji, C.H. Kim, A.E. Greene, R.A. Mulivor, NIGMS Human/Rodent Somatic Cell Hybrid Mapping Panels 1 and 2 Genomics. ,vol. 16, pp. 311- 314 ,(1993) , 10.1006/GENO.1993.1190
W. Allen Hauser, Leonard T. Kurland, The epidemiology of epilepsy in Rochester, Minnesota, 1935 through 1967. Epilepsia. ,vol. 16, pp. 1- 66 ,(1975) , 10.1111/J.1528-1157.1975.TB04721.X
W.-P. Yang, P. C. Levesque, W. A. Little, M. L. Conder, F. Y. Shalaby, M. A. Blanar, KvLQT1, a voltage-gated potassium channel responsible for human cardiac arrhythmias Proceedings of the National Academy of Sciences of the United States of America. ,vol. 94, pp. 4017- 4021 ,(1997) , 10.1073/PNAS.94.8.4017
Stephen G. Ryan, Max Wiznitzer, Charlotte Hollman, M. Cristina Torres, Maria Szekeresova, Sandra Schneider, Benign familial neonatal convulsions: Evidence for clinical and genetic heterogeneity Annals of Neurology. ,vol. 29, pp. 469- 473 ,(1991) , 10.1002/ANA.410290504
A Wei, T JEGLA, L SALKOFF, Eight potassium channel families revealed by the C. elegans genome project Neuropharmacology. ,vol. 35, pp. 805- 829 ,(1996) , 10.1016/0028-3908(96)00126-8
Alain Malafosse, Marion Leboyer, Olivier Dulac, Yvonne Navelet, Perrine Plouin, Corinne Beck, Hassan Laklou, Genevi�ve Mouchnino, Pierre Grandscene, Louis Vallee, Michel Guilloud-Bataille, Dani�le Samolyk, Michel Baldy-Moulinier, Josu� Feingold, Jacques Mallet, Confirmation of linkage of benign familial neonatal convulsions to D20S19 and D20S20. Human Genetics. ,vol. 89, pp. 54- 58 ,(1992) , 10.1007/BF00207042