The beneficial effects of taurine to counteract sarcopenia

摘要: Aging is a multifactorial process characterized by several features including low-grade inflammation, increased oxidative stress and reduced regenerative capacity, which ultimately lead to alteration in morpho-functional properties of skeletal muscle, thus promoting sarcopenia. This condition gradual loss muscle mass due an unbalance between protein synthesis degradation, finally conveying functional decline disability. The development specific therapeutic approaches able block or reverse this may represent invaluable tool for the promotion healthy aging among elderly people. It well established that changes quantity quality dietary proteins, as intake amino acids, are counteract some physiopathological processes related progression have beneficial effects improving anabolic response elderly. Taurine non-essential acid expressed high concentration mammalian tissues particularly where it involved modulation intracellular calcium ion channel regulation also acts antioxidant anti-inflammatory factor. aim review summarize pleiotropic taurine on targets discuss its role regulating signaling pathways maintenance homeostasis. We highlight potential use molecule amelioration function performance severely compromised during aging.