Cellular hypersensitivity and inflammation.

摘要: Cellular hypersensitivity (cell-mediated immunity) is an immunologic reaction that dependent upon the activity of sensitized lymphocytes rather than specific immunoglobulin. In most cases do not act directly as effectors, but elaborate soluble products which are known lymphokines. The classic example a cell-mediated immune “delayed hypersensitivity,” cutaneous manifestation this form response. It also referred to, especially in older literature, “tuberculin” type hypersensitivity. delayed slowly evolving inflammatory (24–48 h to reach maximal size) develops at site injection antigen into previously individual. appears grossly indurated lump and microscopically, least man guinea pig, collection macrophages usually collectively “mononuclear” cells. can be transferred normal, nonimmune individual by lymphocytes, serum.