Effect of titanium surface topography on plasma deposition of antibacterial polymer coatings

摘要: Abstract Plasma processing, e.g., functionalisation and deposition of antibacterial coatings, is often used to enhance surface properties biomaterials. is, however, a non-uniform active medium, the result processing depends on nature both plasma substratum. Here we show that when an coating (i.e., polyterpenol) polymerised onto four types titanium substrata differ in their micro- nano-scale topography (but not bulk chemistry), distribution functional groups, OH C O, polymer across differs sufficiently, so does activity resulting material system. While addition hinders biofilm formation by Staphylococcus aureus Pseudomonas aeruginosa, bactericidal effect significantly stronger polymers deposited surfaces possessing lower degrees nanoscale roughness, after mechanical chemical polishing. The reduced efficacy with greater roughness (e.g., mechanically polished or lotus leaf-like surfaces) attributed extent thickness non-uniformity heterogeneity group surface. These findings suggest magnitude topographical features substratum should be considered designing plasma-enabled modification strategies.