作者: Herbert Meltzer
DOI: 10.1001/ARCHPSYC.1969.01740190104015
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摘要: ACOMMON expression of the disease process in an organ is spilling large amounts normally intracellular enzymes into circulation. For example, increased serum activity creatine kinase (CPK) and aldolase, two soluble cytoplasmic muscle brain, has diagnostic prognostic significance skeletal or cardiac disease, particularly myopathies myocardial infarction, both. 1,2 Recent reports indicate that increases these can also occur some patients with such neurologic psychiatric disorders as brain trauma, cerebral vascular encephalitis, meningitis, acute psychosis. 3-10 Three latter studies relevant to investigations reported here. Schiavone Kaldor found elevated CPK 60% 109 dysfunction, including nine 24 cases schizophrenia. 4 Bengzon et al, after finding elevation alkaline