The controversial role of food allergy in infantile colic: evidence and clinical management.

摘要: Food allergies (FAs) are an increasing problem in Western countries, affecting up to 10% of young children. FAs frequently associated with gastrointestinal manifestations. The role as a potential causative factor for infantile colic (IC) is still controversial. We report the most recent evidence on pathogenesis, clinical and diagnostic aspects FA-induced suggest stepwise approach. selected articles immunologic features, pathogenesis management IC from 1981 2015. Original review were identified through selective searches performed PubMed, using following terms: colic, food allergy treatment. possible relationship between derives presence dysmotility visceral hypersensitivity dysbiosis, demonstrated both conditions, response dietary interventions. Unfortunately, design studies, poor characterization atopy different approaches limit understanding importance subjects IC. without other symptoms remains However, where there suspicion FAs, short trial extensively hydrolyzed cow’s proteins formula or, if breast fed, maternal elimination diet may be considered reasonable option.