Novel hydrazone moiety-bearing aminopyrimidines as selective inhibitors of epidermal growth factor receptor T790M mutant.

作者: Hongbo Xie , Ping Gong , Yanfang Zhao , Mingze Qin , Tingting Wang

DOI: 10.1016/J.EJMECH.2015.09.031

关键词:

摘要: The epidermal growth factor receptor (EGFR) T790M mutant is found in approximately 50% of clinically acquired resistance to gefitinib among patients with non-small cell lung cancer (…

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