作者: Mayienne Bakkers , Catharina G. Faber , Martine J. H. Peters , Jos P. H. Reulen , Hessel Franssen
DOI: 10.1111/JNS5.12001
关键词:
摘要: The diagnosis of small fiber neuropathy (SFN) has been recently defined as typical symptoms due to nerve dysfunction accompanied by reduced intra-epidermal density (IENFD) or abnormal temperature threshold testing (TTT). Guidelines have published for the assessment IENFD. However, international guidelines TTT are lacking. This paper presents a systematic literature review on reported methods and provides recommendations its future use in studies evaluating patients. A total 164 papers fulfilled pre-defined requirements were selected review. Over 15 types instruments currently being used with variety methodological approaches location, stimulus application, sensation qualities examined. Consensus is needed standardize diagnostic follow-up tool