Evolving applications of microarray technology in postnatal diagnosis (review).

摘要: Microarray-based cytogenetics is revealing the tremendous fluidity and complexity of human genome, starting to illustrate implications genomic variability with respect health disease. In last few years, robustness array-based technologies has provided accurate diagnosis appropriate clinical management in a timely efficient manner for identifying defects congenital developmental abnormalities including delay (DD), intellectual disability (ID), autism spectrum disorders (ASD) and/or multiple anomalies (MCA). The implementation this technology these categories been thoroughly evaluated now recommended as first-line diagnostic approach clinically suspected genetic disorders. However, application array-CGH postnatal evaluation raises debate whether will replace traditional near future there still role karyotyping FISH. article, we therefore review current status use predict that it standard test population groups.