Novel functionalized 5-(phenoxymethyl)-1,3-dioxane analogs exhibitng cytochrome p450 inhibition
作者： Magid A Abou-Gharbia , Rajashekar Reddy Nimmareddy , Ramreddy Bobbala , Pravin Iyer , Benjamin Eric Blass
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摘要: Pharmaceutical compositions described in this document comprise 5-(phenoxymethyl)-1,3-dioxane analogs having a disease-modifying action the treatment of diseases associated with production cortisol that include metabolic syndrome, obesity, headache, depression, hypertension, diabetes mellitus, Cushing's Syndrome, pseudo-Cushing cognitive impairment, dementia, heart failure, renal psoriasis, glaucoma, cardiovascular disease, cancer, stroke, incidentalomas, or any involving overproduction cortisol.
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