Human insulin receptor and its relationship to the tyrosine kinase family of oncogenes
作者： A. Ullrich , J. R. Bell , E. Y. Chen , R. Herrera , L. M. Petruzzelli
DOI: 10.1038/313756A0
关键词:
摘要: We have deduced the entire 1,370-amino-acid sequence of human insulin receptor precursor from a single complementary DNA clone. The starts with 27-amino-acid signal sequence, followed by α-subunit, processing enzyme cleavage site, then β-subunit containing 23-amino-acid transmembrane sequence. There are homologies to epidermal growth factor and members src family oncogene products.
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