The origin and erratic global spread of tuberculosis : How the past explains the present and is the key to the future

摘要: Although tuberculosis is a disease known in antiquity, it was not distributed equally or simultaneously throughout the world. Recent genetic studies of various species mycobacteria give strong evidence evolution M. from saprophytic soil bacteria to bovis, which attacks wide spectrum lower animals, and then tuberculosis, with pathogenicity largely limited humans. The great discrepancies time arrival this organism diverse parts world, its ability kill young, account for significant differences emergence innate resistance populations. Innate particular infections are highly specific, derived whatever scourge one's ancestors had survive.