Phenotypic heterogeneity in fungi: importance and methodology

摘要: Phenotypic heterogeneity describes the variation that exists between individual cells, spores or other biological entities within genetically-uniform populations of fungi organisms. Studies over last 10–-15 years have successfully used laboratory- and modelling-based approaches to demonstrate prevalence phenotypic characterise molecular bases phenomenon (primarily centred around heterogeneous gene expression). In contrast progress in these areas, relevance for competitive success organisms different natural scenarios, although widely speculated upon, has only recently begun be investigated. This focus review addresses this latter question as tackled recent studies with yeasts filamentous fungi. We concentrate on fungal activities such survival against environmental stressors, pathogenesis, spoilage. also discuss methodologies interrogating The emerging apparent importance provides a timely reminder certain, potentially core aspects biology still remain under-explored.