Postmortem histopathology of electroencephalography and evoked potentials in postanoxic coma.

作者: Michel J.A.M. van Putten , Casper Jansen , Marleen C. Tjepkema-Cloostermans , Tim M.J. Beernink , Rob Koot

DOI: 10.1016/J.RESUSCITATION.2018.12.007

关键词:

摘要: Abstract Early EEG patterns and SSEP responses are associated with neurological recovery of comatose patients postanoxic encephalopathy after cardiac arrest. However, the nature distribution brain damage underlying characteristic unknown. We relate findings results from histological analyses brains eleven non-survivors. With restoration towards continuous rhythms within 24 h arrest, no signs structural neuronal were observed. Absent always accompanied by thalamic damage. Pathological burst suppression a variable degree to cortex, cerebellum hippocampus. In additional involvement, burst-suppression identical bursts was observed, pattern presumably reflecting residual activity relatively isolated severely compromised cortex.

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