Protective role of myricetin on markers of oxidative stress in human erythrocytes subjected to oxidative stress.
作者： Kanti Bhooshan Pandey , Neetu Mishra , Syed Ibrahim Rizvi
DOI: 10.1177/1934578X0900400211
关键词:
摘要: The protective effect of myricetin against tert-butylhydroperoxide (t-BHP) induced oxidative stress in human erythrocytes was investigated. Incubating with t-BHP (10(-5) M) caused development stress, as evidenced by significant (p < 0.05) increase erythrocyte malondialdedyde (MDA) and protein carbonyl content, decrease intracellular reduced glutathione (GSH), membrane sulphydryl (-SH) groups. Incubation myricetin, simultaneously t-BHP, protected the from an which dose-dependent. results demonstrate that attenuates damage, suggesting supplementation diet myricetin/myricetin rich food may be beneficial all pathological conditions where antioxidant system body is overwhelmed.
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