Analyses of size and computed tomography densitometry parameters for prediction of keloid recurrence after postoperative electron beam radiation therapy.

摘要: BACKGROUND The lesion size is a risk factor for keloid recurrence after postoperative radiotherapy. However, it remains unclear whether the major axis diameter most appropriate parameter to evaluate size, because keloids are often irregular in shape. Additionally, no previous study has investigated computed tomography (CT) densitometry parameters of as potential predictors MATERIALS AND METHODS and CT were measured 74 lesions with images sufficient quality evaluation. association between or was analyzed 64 that could be followed up 6 months more. RESULTS diameter × minor diameter × thickness showed strongest correlation volume (ρ = 0.96, P < .0001). median follow-up period 71 months, 17 recurred. ≥2.5 cm3 (hazard ratio = 5.9, P = .0052) ≥1.2 ml ratio = 4.3, P = .029) significantly associated under multivariate analyses, while alone not. mean maximum values, kurtosis skewness density histogram not different recurrent non-recurrent lesions. CONCLUSION may better than alone. analyses help predict electron beam