Non-invasive localization of atrial ectopic beats by using simulated body surface P-wave integral maps

作者: Ana Ferrer-Albero , Eduardo J. Godoy , Miguel Lozano , Laura Martínez-Mateu , Felipe Atienza

DOI: 10.1371/JOURNAL.PONE.0181263

关键词:

摘要: Non-invasive localization of continuous atrial ectopic beats remains a cornerstone for the treatment arrhythmias. The lack accurate tools to guide electrophysiologists leads an increase in recurrence rate ablation procedures. Existing approaches are based on analysis P-waves main characteristics and forward body surface potential maps (BSPMs) or inverse estimation electric activity heart from those BSPMs. These methods have not provided efficient systematic tool localize triggers. In this work, we propose use machine learning techniques spatially cluster classify foci into clearly differentiated regions by using P-wave integral map (BSPiM) as biomarker. Our simulated results show that with similar BSPiM naturally non-intersected new patterns could be correctly classified accuracy 97% when considering 2 clusters 96% 4 clusters. also suggest number is feasible at cost decreasing accuracy.

参考文章(53)
Peter M. Kistler, Kurt C. Roberts-Thomson, Haris M. Haqqani, Simon P. Fynn, Suresh Singarayar, Jitendra K. Vohra, Joseph B. Morton, Paul B. Sparks, Jonathan M. Kalman, P-Wave Morphology in Focal Atrial Tachycardia: Development of an Algorithm to Predict the Anatomic Site of Origin Journal of the American College of Cardiology. ,vol. 48, pp. 1010- 1017 ,(2006) , 10.1016/J.JACC.2006.03.058
Martin W. Krueger, Viktor Schmidt, Catalina Tobón, Frank M. Weber, Cristian Lorenz, David U. J. Keller, Hans Barschdorf, Michael Burdumy, Peter Neher, Gernot Plank, Kawal Rhode, Gunnar Seemann, Damien Sanchez-Quintana, Javier Saiz, Reza Razavi, Olaf Dössel, Modeling atrial fiber orientation in patient-specific geometries: a semi-automatic rule-based approach international conference on functional imaging and modeling of heart. pp. 223- 232 ,(2011) , 10.1007/978-3-642-21028-0_28
Vincent Jacquemet, Modeling left and right atrial contributions to the ECG Computers in Biology and Medicine. ,vol. 65, pp. 192- 199 ,(2015) , 10.1016/J.COMPBIOMED.2015.06.007
DANIELE GIACOPELLI, JOHN P. BOURKE, ALAN MURRAY, PHILIP LANGLEY, Spatial pattern of P waves in paroxysmal atrial fibrillation patients in sinus rhythm and controls. Pacing and Clinical Electrophysiology. ,vol. 35, pp. 819- 826 ,(2012) , 10.1111/J.1540-8159.2012.03428.X
Ana Ferrer, Rafael Sebastián, Damián Sánchez-Quintana, José F. Rodríguez, Eduardo J. Godoy, Laura Martínez, Javier Saiz, Detailed Anatomical and Electrophysiological Models of Human Atria and Torso for the Simulation of Atrial Activation PLOS ONE. ,vol. 10, pp. e0141573- 29 ,(2015) , 10.1371/JOURNAL.PONE.0141573
Edward P. Gerstenfeld, Arne SippensGroenewegen, Robert L. Lux, Micheel D. Lesh, Derivation of an optimal lead set for measuring ectopic atrial activation from the pulmonary veins by using body surface mapping. Journal of Electrocardiology. ,vol. 33, pp. 179- 185 ,(2000) , 10.1054/JELC.2000.20307
Han S. Lim, Stephan Zellerhoff, Nicolas Derval, Arnaud Denis, Seigo Yamashita, Benjamin Berte, Saagar Mahida, Darren Hooks, Nora Aljefairi, Ashok J. Shah, Frédéric Sacher, Meleze Hocini, Pierre Jais, Michel Haissaguerre, Noninvasive Mapping to Guide Atrial Fibrillation Ablation Cardiac Electrophysiology Clinics. ,vol. 7, pp. 89- 98 ,(2015) , 10.1016/J.CCEP.2014.11.004
Olaf Dössel, Martin W Krueger, Frank M Weber, Mathias Wilhelms, Gunnar Seemann, None, Computational modeling of the human atrial anatomy and electrophysiology Medical & Biological Engineering & Computing. ,vol. 50, pp. 773- 799 ,(2012) , 10.1007/S11517-012-0924-6