Risk of exposure to blood products during pregnancy: guidance for Zika and other donor deferral policies.

摘要: Background Exposure to blood products during pregnancy carries a potential risk of transfusion transmission infectious agents. Blood agencies have historically sought optimal deferral and testing strategies protect supplies in part ensure the protection pregnant women their unborn infants. The Zika virus outbreak 2016 has heightened attention these concerns. In current context recent outbreak, also more broadly, data are needed shed light on likelihood exposure throughout inform policy. Study design methods Hospital administrative from large tertiary care center were examined for outpatient nondelivery inpatient events between January 1, 2007, December 31, 2013. Those pregnancies resulting miscarriage excluded analysis. Results A total 45,179 delivery live or stillborn infant documented at Ottawa study period. Our findings indicate that 0.124%, 1240 1,000,000, expectant mothers received some point with 0.04%, 400 per receiving first trimester. Conclusion Data suggest maternal fetal by any stage is very low. Such low should be taken into consideration when developing donor policies designed against transfusion-associated infection could evaluations prenatal virus.