Inferotemporal-frontal disconnection and fornix transection in visuomotor conditional learning by monkeys

摘要: Abstract The first 2 experiments examined the ability of monkeys ( Macaca fasicularis ) to learn a series visuomotor conditional discrimination problems for food reward. In each problem there were visual stimuli, which different from those in any previous problem. Each trial within presented either one stimulus or other, and indicated motor responses, tap hold, was correct; responses defined such way as be mutually exclusive. Successive trained criterion correct performance. experiment, it found that fornix transection did not impair monkey's learning rate this task. This result contrasts with results showing an impairment following visuo-motor discriminations differentiated other by their spatial position direction. present shows earlier demonstrated impairments are specific responses. second task impaired combination unilateral inferotemporal ablation, contralateral hand used animal, anterior corpus callosum. suggests cortico-cortical interaction between area frontal lobe use is necessary efficient third experiment simultaneous 2-choice animals had participated 2. contrast Expt. 2, unimpaired. Experiment 3 observed general learning.