Prognostic factors for hypopharyngeal cancer: a univariate and multivariate study of 142 cases.

作者: Masato Mochiki , Masashi Sugasawa , Ken-Ichi Nibu , Masao Asai , Kazunari Nakao

DOI: 10.1080/03655230701600095

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摘要: Conclusions. Reduction of distant metastases is essential for better survival. Effective adjuvant chemotherapy should be developed patients with advanced primary disease (T>2) as well nodal status (N>0 or PLN>2). Objectives. The aim this study was to identify prognostic factors hypopharyngeal cancer. Patients and methods. In all, 142 previously untreated were analyzed retrospectively; 75% the cases stage III IV. Surgical resection administered treatment 116 (82%), while 26 (18%) underwent radiotherapy. Results. cause-specific 5-year actuarial survival 46.3%. Distant most frequent (23%) cause failure, followed by local recurrence (15%), regional (13%). Cox's regression analysis showed that significant affecting N classification, T number pathological lymph node (PLN), lymphatic inv...

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