Hypertension-related morbidity and mortality in African Americans--why we need to do better.

摘要: Almost one third of adults in the United States have hypertension. Prevalence data among different racial or ethnic groups indicate that a disproportionate number African Americans hypertension compared with non-Hispanic whites and Mexican Americans. Earlier onset high blood pressure greater severity contribute to burden hypertensive target organ damage may be factor shorter life expectancy this population white There is clear need for improved management via therapeutic lifestyle interventions pharmacotherapy. While there some evidence particular antihypertensive agent classes provide pressure-lowering advantages over others, no support withholding agents any class. When given as monotherapy, diuretics calcium channel blockers relatively more effective lowering than β blockers, angiotensin-converting enzyme inhibitors, angiotensin II receptor blockers. However, when combined diuretic, respond well these other groups. Combination therapy using differing modes action provides additive efficacy tolerated. Recent guidelines recommend combination standard care patients significant elevation, especially those diabetes mellitus renal disease. These comorbidities are common potential initial pill.