GB-C/Hepatitis G Virus bei Hämophilen, Dialysepatienten, HIV-Infizierten und sein Nachweis in Blutprodukten

作者: M. Nübling , J. Löwer

DOI: 10.1007/978-3-642-80403-8_8

关键词:

摘要: Bereits in den 60er Jahren wurde von Deinhardt et al. versucht, im Blut eines amerikanischen Chirurgen mit Initialen G. B., der an Hepatitis erkrankt war, das verantwortliche infektiose Agens zu finden. Dieses Hepatitisagens lies sich zwar aus dem des B. auf Krallenaffchen ubertragen und rief auch bei dieser Spezies Leberentzundungen hervor, doch auser einer groben biologischen Charakterisierung entzog mutmasliche Hepatitisvirus (zumindest vorerst) seiner Entdeckung [3]. Auch die Identifizierung Hepatitisviren A, B D schlieslich C E brachte Folgezeit keine Klarung, da entsprechende Tests GB-Plasma immer negativ ausfielen.

参考文章(14)
Thomas P. Leary, Scott Muerhoff, John N. Simons, Tami J. Pilot-Matias, James C. Erker, Michelle L. Chalmers, George G. Schalauder, George J. Dawson, Suresh M. Desai, Isa K. Mushahwar, Sequence and genomic organization of GBV‐C: A novel member of the flaviviridae associated with human non‐A‐E hepatitis Journal of Medical Virology. ,vol. 48, pp. 60- 67 ,(1996) , 10.1002/(SICI)1096-9071(199601)48:1<60::AID-JMV10>3.0.CO;2-A
Eckart Schreier, Marina Höhne, Udo Künkel, Thomas Berg, Uwe Hopf, Hepatitis GBV-C sequences in patients infected with HCV contaminated anti-D immunoglobulin and among i.v. drug users in Germany Journal of Hepatology. ,vol. 25, pp. 385- 389 ,(1996) , 10.1016/S0168-8278(96)80126-7
Elena R García-Trevijano, Juan M López-Alcorocho, Manuel Quintana, Fernando Hernández, Vicente Carreño, HGV in coagulation-factor concentrates The Lancet. ,vol. 348, pp. 1032- ,(1996) , 10.1016/S0140-6736(05)64959-8
George G. Schlauder, George J. Dawson, John N. Simons, Tami J. Pilot-Matias, Robin A. Gutierrez, Cynthia A. Heynen, Mark F. Knigge, Gretchen S. Kurpiewski, Sheri L. Buijk, Thomas P. Leary, A. Scott Muerhoff, Suresh M. Desai, Isa K. Mushahwar, Molecular and serologic analysis in the transmission of the GB hepatitis agents Journal of Medical Virology. ,vol. 46, pp. 81- 90 ,(1995) , 10.1002/JMV.1890460117
John N. Simons, Thomas P. Leary, George J. Dawson, Tami J. Pilot-Matias, A. Scott Muerhoff, George G. Schlauder, Suresh M. Desai, Isa K. Mushahwar, ISOLATION OF NOVEL VIRUS-LIKE SEQUENCES ASSOCIATED WITH HUMAN HEPATITIS Nature Medicine. ,vol. 1, pp. 564- 569 ,(1995) , 10.1038/NM0695-564
Jeff Linnen, John Wages Jr, Zhen-Yong Zhang-Keck, Kirk E Fry, Krzysztof Z Krawczynski, Harvey Alter, Eugene Koonin, Margaret Gallagher, Miriam Alter, Stephanos Hadziyannis, Peter Karayiannis, Kevin Fung, Yoshiyuki Nakatsuji, J Wai-Kuo Shih, Lavonne Young, Michael Piatak Jr, Cameron Hoover, John Fernandez, Stacie Chen, Jian-Chao Zou, Timothy Morris, Kenneth C Hyams, Susan Ismay, Jeffrey D Lifson, Georg Hess, Steven KH Foung, Howard Thomas, Daniel Bradley, Harold Margolis, Jungsuh P Kim, Molecular Cloning and Disease Association of Hepatitis G Virus: A Transfusion-Transmissible Agent Science. ,vol. 271, pp. 505- 508 ,(1996) , 10.1126/SCIENCE.271.5248.505
A S Muerhoff, T P Leary, J N Simons, T J Pilot-Matias, G J Dawson, J C Erker, M L Chalmers, G G Schlauder, S M Desai, I K Mushahwar, Genomic organization of GB viruses A and B: two new members of the Flaviviridae associated with GB agent hepatitis. Journal of Virology. ,vol. 69, pp. 5621- 5630 ,(1995) , 10.1128/JVI.69.9.5621-5630.1995