Synthesis of naucléfine, angustidine, angustine, (±)-13b,14-dihydro-angustine and naulafine
作者： David B. Repke , Jahangir , Robin D. Clark , Janis T. Nelson , David B. MacLean
DOI: 10.1016/S0040-4020(01)80085-5
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摘要: Abstract The lithio derivatives of 3-cyano-4-methylpyridines and 6,7-dihydro-5H-2-pyrindine-4-carbonitrile react with 2,9-bis-(trimethylsilyl)-3,4-dihydropyrido[3,4-b]indolium trifluoromethanesulfonate to form cyclic amidines which, upon hydrolysis oxidation, produce the title alkaloids.
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