The Role of Sublobar Resection in T1 N0 Non-Small-Cell Pulmonary Carcinoma.

作者: Demet Yaldiz , , Funda Cansun Yakut , Seyda Ors Kaya , Soner Gursoy

DOI: 10.5152/TURKTHORACJ.2019.19064

关键词:

摘要: Objectives In this study, we aimed to investigate the effect of resection type on survival in patients with stage IA non-small-cell lung cancer (NSCLC) and other factors affecting prognosis. Materials methods Between January 2005 December 2016, retrospectively screened 269 who were resected having T1N0M0 pulmonary carcinoma. The time after surgery was obtained from National Population Registration System (MERNIS) system. Patients classified according extent resection. Additionally, age, sex, smoking, concomitant disease, histological type, pathological (T1a-T1b-T1c), presence postoperative complications evaluated determine whether they are prognostic or not. Results A lobectomy performed 257 cases (95.5%), a sublobar 12 (4.5%). 5-year 62.5% for lobectomies 73.3% resections. Although better limited resection, it not statistically significant (p=0.301). Histopathological evaluation revealed that 130 (48.3%) had adenocarcinoma, 113 (42.0%) squamous cell carcinoma, 26 (9.7%) types. rate 69.9% adenocarcinoma 53.2% (p=0.036). overall 5- 10-year rates all 65.0% 47.2%, respectively. Conclusion is standard early Thoracic Surgery Department Dr. Suat Seren Chest Diseases Training Research Hospital underwent found be partially survival, but significant. Owing small number cases, think resections should prospectively investigated more extensive series T1 NSCLC.

参考文章(19)
Robert J. Jensik, L. Penfield Faber, Frank J. Milloy, David O. Monson, Segmental resection for lung cancer: A fifteen-year experience The Journal of Thoracic and Cardiovascular Surgery. ,vol. 66, pp. 563- 572 ,(1973) , 10.1016/S0022-5223(19)40590-4
Morgan N. Windsor, Peter V. Goldstraw, Rishendran Naidoo, Surgery in 2013 and beyond. Journal of Thoracic Disease. ,vol. 5, ,(2013) , 10.3978/J.ISSN.2072-1439.2013.07.39
Yoshinobu Ichiki, Takeshi Hanagiri, Tetsuro Baba, Tetsuya So, Kenji Ono, Hidetaka Uramoto, Tomoko So, Mitsuhiro Takenoyama, Kosei Yasumoto, Limited pulmonary resection for peripheral small-sized adenocarcinoma of the lung International Journal of Surgery. ,vol. 9, pp. 155- 159 ,(2011) , 10.1016/J.IJSU.2010.10.011
Raul Barrera, Jorge Morales Fuentes, Lung cancer in women. Lung Cancer: Targets and Therapy. ,vol. 3, pp. 79- 89 ,(2012) , 10.2147/LCTT.S37319
Morihito Okada, Teruaki Koike, Masahiko Higashiyama, Yasushi Yamato, Ken Kodama, Noriaki Tsubota, Radical sublobar resection for small-sized non–small cell lung cancer: A multicenter study The Journal of Thoracic and Cardiovascular Surgery. ,vol. 132, pp. 769- 775 ,(2006) , 10.1016/J.JTCVS.2006.02.063
H. Nakamura, Y. Taniguchi, K. Miwa, Y. Adachi, S. Fujioka, T. Haruki, Y. Takagi, Y. Yurugi, Comparison of the surgical outcomes of thoracoscopic lobectomy, segmentectomy, and wedge resection for clinical stage I non-small cell lung cancer. Thoracic and Cardiovascular Surgeon. ,vol. 59, pp. 137- 141 ,(2011) , 10.1055/S-0030-1250377
Terumoto Koike, Teruaki Koike, Katsuo Yoshiya, Masanori Tsuchida, Shin-ichi Toyabe, Risk factor analysis of locoregional recurrence after sublobar resection in patients with clinical stage IA non–small cell lung cancer The Journal of Thoracic and Cardiovascular Surgery. ,vol. 146, pp. 372- 378 ,(2013) , 10.1016/J.JTCVS.2013.02.057
Ken Kodama, Osamu Doi, Masahiko Higashiyama, Hideoki Yokouchi, Intentional limited resection for selected patients with T1 N0 M0 non-small-cell lung cancer: A single-institution study The Journal of Thoracic and Cardiovascular Surgery. ,vol. 114, pp. 347- 353 ,(1997) , 10.1016/S0022-5223(97)70179-X
Cardinale B. Smith, Scott J. Swanson, Grace Mhango, Juan P. Wisnivesky, Survival After Segmentectomy and Wedge Resection in Stage I Non–Small-Cell Lung Cancer Journal of Thoracic Oncology. ,vol. 8, pp. 73- 78 ,(2013) , 10.1097/JTO.0B013E31827451C4
Robert J Ginsberg, Lawrence V Rubinstein, Lung Cancer Study Group, None, Randomized trial of lobectomy versus limited resection for T1 N0 non-small cell lung cancer The Annals of Thoracic Surgery. ,vol. 60, pp. 615- 623 ,(1995) , 10.1016/0003-4975(95)00537-U