A prospective comparison of totally minimally invasive versus open Ivor Lewis esophagectomy

摘要: The majority of esophagectomies in Western parts the world are performed by a transthoracic approach reflecting prevalence adenocarcinoma lower esophagus or esophagogastric junction. Minimally invasive esophagectomy (MIE) has been reported variety formats, but there no series that directly compare totally minimally thoracolaparoscopic 2 stage (MIE-2) with open Ivor Lewis (IVL). A prospective single-center cohort study patients undergoing elective MIE-2 IVL between January 2005 and November 2010 was performed. Short-term clinicopathologic outcomes were recorded using validated systems. One hundred six (median age 66, range 36–85, 88 M : 18 F) underwent two-stage (53 53 IVL). Patient demographics (age, sex, body mass index, American Society Anesthesiologists grade, tumor characteristics, neoadjuvant chemotherapy, TNM stage) comparable two groups. Outcomes for anastomotic leak rates (5 [9%] vs. [4%], P= 0.241), resection margin clearance (R0) (43 [81%] 38 [72%], 0.253), median lymph node yield (19 18, 0.584), length stay (12 [range 7–91] 12 7–101] days), respectively. Blood loss significantly less compared 300 0–1250] mL 400 0–3000] mL, respectively, 0.021). this selected supports its efficacy, when an experienced surgical team. well-designed multicenter trial addressing clinical effectiveness is now required.