Functional regulation of Slug / Snail2 is dependent on GSK‐3β‐mediated phosphorylation

作者: Jin Young Kim , Young Mee Kim , Chang Hee Yang , Somi K. Cho , Jung Weon Lee

DOI: 10.1111/J.1742-4658.2012.08674.X

关键词:

摘要: … GAPDH and lamin B1 were used as controls for fractionation and for equal loading of … EMT. Our study not only reveals a molecular mechanism underlying Snail2-induced EMT, but also …

参考文章(28)
Xin-Qin Kang, Wei-Jin Zang, Li-Jun Bao, Dong-Ling Li, Tu-Sheng Song, Xiao-Li Xu, Xiao-Jiang Yu, Fibroblast growth factor-4 and hepatocyte growth factor induce differentiation of human umbilical cord blood-derived mesenchymal stem cells into hepatocytes World Journal of Gastroenterology. ,vol. 11, pp. 7461- 7465 ,(2005) , 10.3748/WJG.V11.I47.7461
Sivan Elloul, Ilvars Silins, Claes G. Tropé, Avi Benshushan, Ben Davidson, Reuven Reich, Expression of E-cadherin transcriptional regulators in ovarian carcinoma. Virchows Archiv. ,vol. 449, pp. 520- 528 ,(2006) , 10.1007/S00428-006-0274-6
Y Xu, SH Lee, HS Kim, NH Kim, S Piao, SH Park, YS Jung, JI Yook, BJ Park, NC Ha, None, Role of CK1 in GSK3β-mediated phosphorylation and degradation of Snail Oncogene. ,vol. 29, pp. 3124- 3133 ,(2010) , 10.1038/ONC.2010.77
Chang Hee Yang, Byung-Cheol Song, Moonjae Cho, A natural mutation of the hepatitis B virus X gene affects cell cycle progression and apoptosis in Huh7 cells Journal of The Korean Society for Applied Biological Chemistry. ,vol. 55, pp. 229- 236 ,(2012) , 10.1007/S13765-012-2012-X
Maria J Blanco, Gema Moreno-Bueno, David Sarrio, Annamaria Locascio, Amparo Cano, José Palacios, M Angela Nieto, None, Correlation of Snail expression with histological grade and lymph node status in breast carcinomas. Oncogene. ,vol. 21, pp. 3241- 3246 ,(2002) , 10.1038/SJ.ONC.1205416
Jackie Papkoff, Mina Aikawa, WNT-1 and HGF Regulate GSK3β Activity and β-Catenin Signaling in Mammary Epithelial Cells Biochemical and Biophysical Research Communications. ,vol. 247, pp. 851- 858 ,(1998) , 10.1006/BBRC.1998.8888
Eun-Sil Kang, Dohyun Han, Jungeun Park, Tae Kyoung Kwak, Min-A Oh, Sin-Ae Lee, Suyong Choi, Zee Yong Park, Youngsoo Kim, Jung Weon Lee, O-GlcNAc modulation at Akt1 Ser473 correlates with apoptosis of murine pancreatic β cells Experimental Cell Research. ,vol. 314, pp. 2238- 2248 ,(2008) , 10.1016/J.YEXCR.2008.04.014
Manav Korpal, Yibin Kang, Targeting the transforming growth factor-β signalling pathway in metastatic cancer European Journal of Cancer. ,vol. 46, pp. 1232- 1240 ,(2010) , 10.1016/J.EJCA.2010.02.040
Alessandra Marchetti, Marta Colletti, Angela Maria Cozzolino, Corinna Steindler, Mario Lunadei, Carmine Mancone, Marco Tripodi, ERK5/MAPK is activated by TGFβ in hepatocytes and required for the GSK-3β-mediated Snail protein stabilization Cellular Signalling. ,vol. 20, pp. 2113- 2118 ,(2008) , 10.1016/J.CELLSIG.2008.08.002