Role of external beam radiotherapy with low-dose-rate brachytherapy in treatment of prostate cancer

摘要: Abstract Objectives To report a single-institution experience and analysis of the role supplemental external beam radiotherapy (EBRT) with brachytherapy. EBRT is often used in addition to low-dose-rate brachytherapy treatment prostate cancer, particularly for disease adverse features. Methods A cohort 189 consecutive patients, who had undergone at our institution demographic, disease, information minimum 2 years follow-up available, constituted study group. This was divided into two major groups according use EBRT. Using successive prostate-specific antigen rises greater than 1 ng/mL as definition failure, biochemical failure-free survival curves were constructed no-EBRT compared using log-rank test. Additionally, multivariate all factors performed Cox proportional hazards model. Results Despite proportion group, 5-year rate versus 80% 59%, respectively ( P = 0.043). Conclusions In study, conferred significant control advantage when added Because not designed permit detailed subset analyses, more work needed determine precise population that will benefit from this