Long-term Patient Self-management of Oral Anticoagulation
作者： Jack E. Ansell
DOI: 10.1001/ARCHINTE.1995.00430200066010
关键词:
摘要: Background: The management of oral anticoagulation is fraught with difficulties. This study assessed a new model regarding the ability, safety, and efficacy patients to self-monitor self-adjust dose their anticoagulants guided by capillary whole-blood prothrombin time (PT) monitor. Methods: investigation retrospective cohort 20 compared matched control receiving at tertiary medical institution. Results: Study monitored PTs 2153 times during mean interval 44.7 months 1608 in 42.5 months. made an average 11.5 dosage changes per patient, contrasted 22.7 patient ( P Conclusions: Results from what first long-term self-monitoring self-adjustment warfarin sodium for suggest that can successfully measure own PTs, adjust dosage, achieve degree therapeutic effectiveness least as good, if not better than managed anti- coagulation clinic. Larger, prospective, randomized trials are needed confirm safety this approach therapy assess its cost-effectiveness. (Arch Intern Med. 1995;155:2185-2189)
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