Catalyst-free three-component reaction between 2-aminopyridines (or 2-aminothiazoles), aldehydes, and isocyanides in water

作者: Mehdi Adib , Mohammad Mahdavi , Mahsa Alizadeh Noghani , Peiman Mirzaei

DOI: 10.1016/J.TETLET.2007.08.049

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摘要: Abstract A catalyst-free and convenient protocol is described for the preparation of 3-aminoimidazo[1,2- a ]pyridines 5-aminoimidazo[2,1- b ][1,3]thiazoles via three-component reactions between 2-aminopyridines or 2-aminothiazoles, aldehydes, isocyanides in water good to excellent yields.

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