Theories of Aging and the Prevalence of Alzheimer's Disease.
作者： Kaynara Trevisan , Renata Cristina-Pereira , Danyelle Silva-Amaral , Tales Alexandre Aversi-Ferreira
DOI: 10.1155/2019/9171424
关键词:
摘要: Objective. Aging and AD are associated in some way, then it is reasonable to ask whether or not possible age without inexorably appearing at any moment, depending on the period of life. Therefore, goal this review verify, light aging theories, prevalence AD. Methods. For purpose manuscript, indexers Alzheimer, aging, were considered; theories researched. The research was conducted using PubMed, Medline, Scopus, Elsevier, Google Scholar. Results. most common subjects papers analyzed for manuscript Alzheimer’s disease. association between Alzheimer seems inconclusive. Conclusions. Accordingly, general idea that with such a way almost all people will present disease; however, plausible consider increase life expectancy generate high In sense, explain origin under superlative catastrophic considerations use more biomolecular data than social behavioral as bases analysis, which may be problem.
hindawi.com参考文章(110)
Vincent J. Cristofalo, Glenn S. Gerhard, Robert J. Pignolo, Molecular biology of aging. Surgical Clinics of North America. ,vol. 74, pp. 1- 21 ,(1994) , 10.1016/S0039-6109(16)46225-0
E V Kurenova, J M Mason, Telomere functions. A review Biochemistry. ,vol. 62, pp. 1242- 1253 ,(1997)
Blackburn Eh, The telomere and telomerase: nucleic acid-protein complexes acting in a telomere homeostasis system. A review. Biochemistry. ,vol. 62, pp. 1196- 1201 ,(1997)
Karl Herrup, The case for rejecting the amyloid cascade hypothesis Nature Neuroscience. ,vol. 18, pp. 794- 799 ,(2015) , 10.1038/NN.4017
Robin de Flores, Renaud La Joie, Gaël Chételat, Structural imaging of hippocampal subfields in healthy aging and Alzheimer's disease Neuroscience. ,vol. 309, pp. 29- 50 ,(2015) , 10.1016/J.NEUROSCIENCE.2015.08.033
D. Tromp, A. Dufour, S. Lithfous, T. Pebayle, O. Després, Episodic memory in normal aging and Alzheimer disease: Insights from imaging and behavioral studies Ageing Research Reviews. ,vol. 24, pp. 232- 262 ,(2015) , 10.1016/J.ARR.2015.08.006
Jenna M. Tarasoff-Conway, Roxana O. Carare, Ricardo S. Osorio, Lidia Glodzik, Tracy Butler, Els Fieremans, Leon Axel, Henry Rusinek, Charles Nicholson, Berislav V. Zlokovic, Blas Frangione, Kaj Blennow, Joël Ménard, Henrik Zetterberg, Thomas Wisniewski, Mony J. de Leon, Clearance systems in the brain—implications for Alzheimer disease Nature Reviews Neurology. ,vol. 11, pp. 457- 470 ,(2015) , 10.1038/NRNEUROL.2015.119
Bruno Dubois, Alessandro Padovani, Philip Scheltens, Andrea Rossi, Grazia Dell’Agnello, Timely Diagnosis for Alzheimer's Disease: A Literature Review on Benefits and Challenges. Journal of Alzheimer's Disease. ,vol. 49, pp. 617- 631 ,(2015) , 10.3233/JAD-150692
Zhiqiang Xu, Na Xiao, Yali Chen, Huang Huang, Charles Marshall, Junying Gao, Zhiyou Cai, Ting Wu, Gang Hu, Ming Xiao, Deletion of aquaporin-4 in APP/PS1 mice exacerbates brain Aβ accumulation and memory deficits Molecular Neurodegeneration. ,vol. 10, pp. 58- 58 ,(2015) , 10.1186/S13024-015-0056-1
B E Torbett, K Bottomly, M A Rehse, D N Ernst, M V Hobbs, W O Weigle, K Hayakawa, R R Hardy, A L Glasebrook, Differences in the expression profiles of CD45RB, Pgp-1, and 3G11 membrane antigens and in the patterns of lymphokine secretion by splenic CD4+ T cells from young and aged mice. Journal of Immunology. ,vol. 145, pp. 1295- 1302 ,(1990)