Methadone maintenance treatment in opiate dependence: a review

摘要: This paper examines the changes and advances in research clinical practice role of treatment structure programme characteristics delivery methadone maintenance. Methadone prescribing has become much more available over past decade, both countries with a history its use, such as United Kingdom Australia, around world which previously had not endorsed substitute prescribing.1 There is need to examine closely framework this delivered ensure that modes most effective from cost benefit perspectives are utilised. review focuses entirely on maintenance because extensively evaluated used treatment, about quarter million drug misusers receiving globally. A small number experimental diamorphine buprenorphine programmes being several countries. Most studies have come States focus long term use specific setting; contrast, received virtually no formal evaluation date bar one study.2 concern considerable amount could be having little impact illicit or risk taking behaviour,3 recent study users police custody echoes this.4 The Advisory Council Misuse Drugs recommended shift structured approach for oral maintenance. The organisation regulation varies widely, explicit guidelines operation Australia virtual absence Britain. It likely policy analysts providers high levels …