Impaired anastomotic healing after preoperative radiotherapy followd by anterior resection for treatment of rectal carcinoma

作者: Johan F Lange , Jefrey Vermeulen , Erwin van der Harst

DOI: 10.7196/SAJS.82

关键词:

摘要: Background. Patients with rectal carcinoma undergoing total mesorectal excision (TME) have a lower recurrence rate preoperative radiotherapy (RT). The aim of this study was to assess the side-effects in patients who had RT compared those did not receive it (because palliative resections, advanced age or refusal). Methods. From January 2001 March 2003, 40 underwent resection and double-stapled anastomosis for carcinoma. We 17 received followed by low anastomosis, 23 RT. Results. After surgery 7/17 developed anastomotic leaks. Anastomotic leakage seen only once (41% v. 4%, p = 0.006). A protective stoma, which performed 11 group, did prevent (4/11 stoma 3/6 without 0.64). Median hospital stay longer group (17.4 13.7 days, 0.017). There no difference number minor postoperative complications between two groups (24% 22%). Conclusion. Compared alone, short-term increased leaks stay, whether performed.. South African Journal Surgery Vol. 44 (1) 2006: pp. 12-16

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