The processing and characterization of animal-derived bone to yield materials with biomedical applications. Part II: milled bone powders, reprecipitated hydroxyapatite and the potential uses of these materials.

摘要: Further studies on the processing and use of animal-bone-derived calcium phosphate materials in biomedical applications are presented. Bone powders sourced either from direct crushing milling bovine, ovine cervine bone or after being subjected to defatting acid digestion/NaOH reprecipitation sodium hypochlorite hydrogen peroxide treatment animal bones were characterized using Fourier transform infra-red (FTIR) spectroscopy, 13C solid state magic angle spinning (MAS) nuclear magnetic resonance (NMR) atomic absorption (AA) inductively coupled plasma (ICP) spectrometric techniques. trialled for their potential as a substrate phosphine coupling enzyme immobilization well feedstock powder spraying titanium metal substrates. Results indicated that by could be successfully achieved milled with immobilized retaining some activity. It was found presence impurities normally carried down (viz., fat collagen) played an important role influencing adsorbency reactivity powders. Plasma reprecipitated bovine-derived produced highly adherent coatings metal, composition which mostly hydroxyapatite(Ca10(PO4)6(OH)2) low levels α-tricalcium (α-Ca3(PO4)2) tetracalcium (Ca4P2O9) also detected. In general, derived constitute potentially cheaper source make largely under-utilized resource abattoir wastes. © 2000 Kluwer Academic Publishers