Rho guanine nucleotide exchange factors: regulators of Rho GTPase activity in development and disease
作者： D R Cook , K L Rossman , C J Der
DOI: 10.1038/ONC.2013.362
关键词:
摘要: The aberrant activity of Ras homologous (Rho) family small GTPases (20 human members) has been implicated in cancer and other human diseases. However, in contrast to the direct …
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Neal M. Alto, Feng Shao, Cheri S. Lazar, Renee L. Brost, Gordon Chua, Seema Mattoo, Stephen A. McMahon, Partho Ghosh, Timothy R. Hughes, Charles Boone, Jack E. Dixon, Identification of a Bacterial Type III Effector Family with G Protein Mimicry Functions Cell. ,vol. 124, pp. 133- 145 ,(2006) , 10.1016/J.CELL.2005.10.031
H.-X. Deng, H. Zhai, R. Fu, Y. Shi, G. H. Gorrie, Y. Yang, E. Liu, M. C. Dal Canto, E. Mugnaini, T. Siddique, Distal axonopathy in an alsin-deficient mouse model Human Molecular Genetics. ,vol. 16, pp. 2911- 2920 ,(2007) , 10.1093/HMG/DDM251
Shinji Hadano, Susanna C. Benn, Shigeru Kakuta, Asako Otomo, Katsuko Sudo, Ryota Kunita, Kyoko Suzuki-Utsunomiya, Hikaru Mizumura, Jeremy M. Shefner, Gregory A. Cox, Yoichiro Iwakura, Robert H. Brown, Joh-E Ikeda, Mice deficient in the Rab5 guanine nucleotide exchange factor ALS2/alsin exhibit age-dependent neurological deficits and altered endosome trafficking Human Molecular Genetics. ,vol. 15, pp. 233- 250 ,(2006) , 10.1093/HMG/DDI440
Rachel J. Buchsbaum, Beth A. Connolly, Larry A. Feig, Interaction of Rac exchange factors Tiam1 and Ras-GRF1 with a scaffold for the p38 mitogen-activated protein kinase cascade. Molecular and Cellular Biology. ,vol. 22, pp. 4073- 4085 ,(2002) , 10.1128/MCB.22.12.4073-4085.2002
Yeonjoo Jung, Sanghyuk Lee, Hyung-Seok Choi, Soon-Nam Kim, Eunyoung Lee, Youngah Shin, Jihae Seo, Bumjin Kim, Yeonhwa Jung, Wan Kyu Kim, Ho-Kyung Chun, Woo Yong Lee, Jaesang Kim, Clinical Validation of Colorectal Cancer Biomarkers Identified from Bioinformatics Analysis of Public Expression Data Clinical Cancer Research. ,vol. 17, pp. 700- 709 ,(2011) , 10.1158/1078-0432.CCR-10-1300
Bingke Yu, Ilídio R.S. Martins, Pilong Li, Gaya K. Amarasinghe, Junko Umetani, Martin E. Fernandez-Zapico, Daniel D. Billadeau, Mischa Machius, Diana R. Tomchick, Michael K. Rosen, Structural and energetic mechanisms of cooperative autoinhibition and activation of Vav1. Cell. ,vol. 140, pp. 246- 256 ,(2010) , 10.1016/J.CELL.2009.12.033
Richard Bulgin, Benoit Raymond, James A. Garnett, Gad Frankel, Valerie F. Crepin, Cedric N. Berger, Ana Arbeloa, Bacterial Guanine Nucleotide Exchange Factors SopE-Like and WxxxE Effectors Infection and Immunity. ,vol. 78, pp. 1417- 1425 ,(2010) , 10.1128/IAI.01250-09
E J Marco, F E Abidi, J Bristow, W B Dean, P Cotter, R J Jeremy, C E Schwartz, E H Sherr, ARHGEF9 disruption in a female patient is associated with X linked mental retardation and sensory hyperarousal Journal of Medical Genetics. ,vol. 45, pp. 100- 105 ,(2007) , 10.1136/JMG.2007.052324
Huaibin Cai, Xian Lin, Chengsong Xie, Fiona M Laird, Chen Lai, Hongjin Wen, Hsueh-Cheng Chiang, Hoon Shim, Mohamed H Farah, Ahmet Hoke, Donald L Price, Philip C Wong, None, Loss of ALS2 Function Is Insufficient to Trigger Motor Neuron Degeneration in Knock-Out Mice But Predisposes Neurons to Oxidative Stress The Journal of Neuroscience. ,vol. 25, pp. 7567- 7574 ,(2005) , 10.1523/JNEUROSCI.1645-05.2005
Tomoshige Kino, Emanuel Souvatzoglou, Evangelia Charmandari, Takamasa Ichijo, Paul Driggers, Chantal Mayers, Anton Alatsatianos, Irini Manoli, Heiner Westphal, George P Chrousos, James H Segars, None, Rho family Guanine nucleotide exchange factor Brx couples extracellular signals to the glucocorticoid signaling system. Journal of Biological Chemistry. ,vol. 281, pp. 9118- 9126 ,(2006) , 10.1074/JBC.M509339200