REVIEW Behavioral Approaches to Toluene Intoxication

摘要: Toluene is a chemical that very useful in our lives but harmful to health. Behavioral toxicology has the merit of providing an accurate indication functional toxicity CNS through analysis learned behavior and use behavioral techniques give us various learning paradigms for investigating effects chemicals on memory, stimulus discrimination, attention, time perception, etc. Learning common ability among species it possible predict human health from animals. assumed play important role occupational environmental Using typical test batteries such as shuttle, Sidman, pole-climb avoidance, FI, FR, DRL, DMS tasks, toluene were investigated results reviewed. One objective battery be able detect already-known toxicity. research indicated hyperactivity, ataxia, addiction, insomnia, memory disturbances. Some excellent which might indicate clinically unknown hearing loss, impairments improvements STM also demonstrated. Introduction blood brain levels index exposure more sophisticated tasks reflect specific higher nervous functions been proposed. © 1993 Academic Press, Inc.