Evaluation of fluorimetrically estimated serum bile acid in liver disease

摘要: Fasting serum bile acid (SBA) was measured by the enzymic fluorimetric method coupled with NAD-resazurin system in 23 controls, 35 asymptomatic carriers of HIs antigen including 4 e and 91 patients various liver diseases. All GHBs showed SBA within normal range. most significantly correlated bilirubin (gamma=0.74) a more sensitive index for impaired function than or alkaline phosphatase 164 radomly chosen samples from disease group. In serial determinations reference to GOT, GPT, changing patterns these two parameters were classified into parallel type discrepant type. Thirty out 40 cases chronic belonged remained abnormal even after normalization transaminase 12 20 resolving episodes type, regardless diagnosis. Since changes according stage activity, simultaneous estimation GPT found be helpful observation Maximum values elevation an endogenous tolerance test eating egg yolks higher controls 7 disease, who associated fasting SBA.