The transcription-independent mitochondrial p53 program is a major contributor to nutlin-induced apoptosis in tumor cells.
作者： Angelina V. Vaseva , Natalia D. Marchenko , Ute Moll
DOI: 10.4161/CC.8.11.8596
关键词:
摘要: … Nutlin is a potent and selective pharmacological MDM2 inhibitor that competitively binds to … translocation is associated with markedly depressed mitochondrial Cytochrome C release …
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