Chemical composition and pharmacological properties of the essential oils obtained seasonally from Lippia thymoides

作者: Fabrício Souza Silva , Pedro Modesto Nascimento Menezes , Pedro Guilherme Souza de Sá , André Luís de Santana Oliveira , Eric Alencar Araújo Souza

DOI: 10.3109/13880209.2015.1005751

关键词:

摘要: AbstractContext: Lippia thymoides Mart. & Schauer (Verbenaceae) is used in folk medicine to treat wounds, fever, bronchitis, rheumatism, headaches, and weakness.Objective: This study determinates the chemical composition of essential oils from L. thymoides, obtained at during each four seasons correlates with pharmacological properties.Materials methods: Essential were by hydrodistillation analyzed gas chromatography coupled mass spectroscopy (GC-MS). Antioxidant activity was determined DPPH free radical scavenging β-carotene bleaching methods. The antimicrobial assays performed minimum inhibitory concentration (MIC) microbicidal (MMC) Isolated rat aorta uterus, guinea-pig trachea utilized evaluate relaxant potential pre-contracted smooth muscle.Results discussion: leaves had sesquiterpene β-caryophyllene (17.22–26.27%) as major constituent followed by...

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