Preparation of hepatitis b surface antigen in yeast

作者: Ronald A. Hitzeman , Arthur D. Levinson , Daniel G. Yansura

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摘要: Hepatitis surface antigen is synthesized in recombinant yeast hosts transformed with vectors encoding hepatitis antigen, preferably under the control of PGK promoter and absence DNA precursor. assembled by into antigenic 22 nm particles even though bacterial transformants were not known to be capable assembling particles.

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