Sequential Processes in Palladium-Catalyzed Silicon-Based Cross-Coupling

摘要: Although developed somewhat later, silicon-based cross-coupling has become a viable alternative to the more conventional Suzuki-Miyaura, Stille-Kosugi-Migita, and Negishi reactions because of its broad substrate scope, high stability silicon-containing reagents, low toxicity waste streams. An empowering yet underappreciated feature unique is wide range sequential processes available. In these processes, simple precursors are first converted complex substrates, subsequent reaction affords an even highly functionalized product in stereoselective fashion. so doing, structurally inexpensive starting materials quickly transformed into value-added densely substituted products. Therefore, often useful constructing carbon backbones natural this review, studies involving discussed. Additionally, total syntheses that utilize also presented.