Bridged Nucleic Acids: Development, Synthesis and Properties
作者： Satoshi Obika , SM Abdur Rahman , Aki Fujisaka , Yuji Kawada , Takeshi Baba
DOI: 10.3987/REV-10-667
关键词:
摘要: Restricting the sugar moiety of a nucleic acid to single conformation can be accomplished by forming bridge in sugar. A large number bridged acids with variable structures and conformations have been developed. The synthesis properties these artificial analogues are discussed. Such conformational restriction significantly improved acid.
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