A Prospective Study on Adverse Drug Reactions in a Tertiary Care South Indian Hospital
作者： ArulKumaran Ksg , Palanisamy S , Rajasekaran A
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摘要: Background: ADRs have a major impact on public health, reducing patients' quality of life and imposing considerable financial burden the health care systems. Objectives: The main objectives were to analyze pattern extent occurrence in hospital, identify co-morbidities, past present illness, assess causality offending drugs, severity preventability adverse drug reactions. Methods: Prospective, observational, spontaneous, reporting study with both active passive methods. Results: A prospective observational spontaneous was carried out from January 2009 August 2012. total 950 accepted reported 1227 ADRs. Female patients experienced more number when compared male patients. Fever most commonly observed reason for admission. Maculopapular skin rashes ADR population. Amoxicillin Clavulanic acid combination implicated antibiotic category than others. Sixty one percent moderate followed by minor severe Most reactions population managed withdrawing rechallenge performed few subjects. definitely preventable (40%) predictable nature. Eighty probably related 758 likely cause Twenty five treated symptomatically
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