Disseminated Strongyloides stercoralis in Human Immunodeficiency Virus-infected Patients: Treatment Failure and a Review of the Literature

作者: Klaus-Dieter Lessnau , Selcuk Can , Wilfredo Talavera

DOI: 10.1378/CHEST.104.1.119

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摘要: We describe a North American human immunodeficiency virus (HIV)-positive patient with Strongyloides stercoralis infection of the gastrointestinal tract, who required repeated "standard" courses thiabendazole. Pulmonary numerous roundworms developed, as suspected by bronchoalveolar lavage, and while he was receiving therapy, dissemination occurred. On autopsy, S recovered in liver, lung, heart. After literature review, we conclude that HIV-positive patients have higher risk treatment failure. This may occur without elevation IgE or eosinophilia. Those require prolonged thiabendazole alternatively ivermectin therapy.

参考文章(16)
MORDECHAI R. KRAMER, PATRICIA A. GREGG, MICHAEL GOLDSTEIN, ROBERTO LLAMAS, BRUCE P. KRIEGER, Disseminated strongyloidiasis in AIDS and non-AIDS immunocompromised hosts: diagnosis by sputum and bronchoalveolar lavage. Southern Medical Journal. ,vol. 83, pp. 1226- 1229 ,(1990) , 10.1097/00007611-199010000-00024
Orlando Armignacco, Antonio Capecchi, Patrizia De Mori, Lucia R. Grillo, Strongyloides stercoralis hyperinfection and the acquired immunodeficiency syndrome. The American Journal of Medicine. ,vol. 86, pp. 258- ,(1989) , 10.1016/0002-9343(89)90290-8
Mark M. Gompels, Jeannie Todd, Barry S. Peters, Janice Main, Anthony J. Pinching, Disseminated strongyloidiasis in AIDS: uncommon but important. AIDS. ,vol. 5, pp. 329- 332 ,(1991) , 10.1097/00002030-199103000-00015
George A. DeVault, John W. King, Michael S. Rohr, Michael D. Landreneau, Stephen T. Brown, John C. McDonald, Opportunistic Infections with Strongyloides stercoralis in Renal Transplantation Clinical Infectious Diseases. ,vol. 12, pp. 653- 671 ,(1990) , 10.1093/CLINIDS/12.4.653
Edward Chu, Warren L. Whitlock, Robert A. Dietrich, Pulmonary Hyperinfection Syndrome with Strongyloides stercoralis Chest. ,vol. 97, pp. 1475- 1477 ,(1990) , 10.1378/CHEST.97.6.1475
ERIC B. SCOWDEN, WILLIAM SCHAFFNER, WILLIAM J. STONE, Overwhelming strongyloidiasis: an unappreciated opportunistic infection. Medicine. ,vol. 57, pp. 527- 544 ,(1978) , 10.1097/00005792-197811000-00004
Shlomo Maayan, Gary P. Wormser, Josef Widerhorn, Ernsto R. Sy, Ye H. Kim, Jerome A. Ernst, Strongyloides stercoralis hyperinfection in a patient with the acquired immune deficiency syndrome The American Journal of Medicine. ,vol. 83, pp. 945- 948 ,(1987) , 10.1016/0002-9343(87)90656-5
Liliane Schainberg, Morton A. Scheinberg, Recovery of Strongyloides stercoralis by bronchoalveolar lavage in a patient with acquired immunodeficiency syndrome. The American Journal of Medicine. ,vol. 87, pp. 486- 486 ,(1989) , 10.1016/S0002-9343(89)80846-0
J N Harcourt-Webster, F Scaravilli, A H Darwish, Strongyloides stercoralis hyperinfection in an HIV positive patient. Journal of Clinical Pathology. ,vol. 44, pp. 346- 348 ,(1991) , 10.1136/JCP.44.4.346