FDG-PET for prediction of survival of patients with metastatic colorectal carcinoma.

作者: L.F. de Geus-Oei , B. Wiering , P.F.M. Krabbe , T.J.M. Ruers , C.J.A. Punt

DOI: 10.1093/ANNONC/MDL180

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摘要: colorectal cancer. Patients and methods: In a prospective series of 152 patients with metastatic cancer, whom 67 were treated resection metastases 85 chemotherapy, standardized uptake values (SUV) as measured FDG-PET, calculated prior to treatment. Survival probabilities estimated by Cox proportional regression analysis. For Kaplan–Meier analysis SUV was stratified the median value. differences assessed using log-rank test. Results: in significant predictor for overall survival (hazard ratio 1.17, 95% confidence interval 1.06–1.30, P = 0.002), independent subsequent According value patient population low (SUV 4.26) defined. The 2- 3-year rates 32 months, 59% 45%, respectively, low-uptake group 19 37% 28%, high-uptake (P 0.017). Conclusion: A benefit observed FDG

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