“TEG talk”: expanding clinical roles for thromboelastography and rotational thromboelastometry

摘要: Viscoelastic assays (VEAs) that include thromboelastography and rotational thromboelastometry add value to the investigation of coagulopathies goal-directed management bleeding by providing a complete picture clot formation, strength, lysis in whole blood includes contribution platelets, fibrinogen, coagulation factors. Conventional have several limitations, such as their lack correlation with hypercoagulability; inability reflect factor XIII, plasmin during formation lysis; slow turnaround times. VEA-guided transfusion algorithms may reduce allogeneic exposure after cardiac surgery emergency trauma-induced coagulopathy hemorrhage. However, popularity VEAs for other indications is driven largely extrapolation evidence from surgery, drawbacks conventional assays, institution-specific preferences. Robust diagnostic studies validating standardizing cutoffs VEA parameters randomized trials comparing standard care on clinical outcomes are urgently needed. Lack represents biggest barrier defining role impact care.