Synthèse stéréosélective des sulfones vinyliques Z et E.

摘要: Abstract The condensation of α-sulphonyl carbanions with esters or aldehydes (followed in this case by oxidation) gives β-ketosulphones. These were reduced stereoselectively into threo β-hydroxysulphones. Basic conditions have been found where the corresponding tosylates are converted Z vinylic sulphones whereas erythro lead to E isomer. acetoxy-sulphones threo, under different alkaline same sulphone a “convergent” manner.