Variations in the Transmission Ratios of Alleles Through Egg and Sperm in Mus musculus

摘要: The most striking fact about Mendel's principle of segregation is the universality its application. It co-extensive with genes, and genes as we know are life. In a sense, whole structure genetics arose from this principle; who ply trade have had our ways thinking so conditioned by it that when there rumors an exception to has been found, feel earth quaking beneath us. These usually turn out be groundless but they generate salutary effect: in process finding not itself at fault led discover hitherto unsuspected which affect living processes. shock thus attributable discovery knowledge faulty defect order nature on come depend. case I am going describe morning run through part gamut. When some 20 years ago became apparent male mice were transmitting certain ratios quite other than those called for normal operation mechanism could regarded laboratory curiosity or anomaly few animals obscure meiotic irregularity. pretty sad meek figures anyway, having no tails variety abnormalities connected condition would prevent them ever cutting much figure nature. They did provide good material 'interested control developmental processes, especially early embryos, experimental embryologists didn't like because inaccessibility cytologists their chromosomes small well differentiated. And developed same abnormal both lethal common populations wild house mice, made bid low regard population geneticists well. For here refused distribute bionomial calculus