Молекулярные и клеточные механизмы действия синглетного кислорода на биосистемы

摘要: There has been considered a poorly studied form of activated oxygen singlet oxygen. Its physicochemical properties (electron configuration molecule, reactive capacity, features) are analyzed, and enzymic nonenzymic ways generation in body specified. shown detail biological effects the compound as regulator cell activity including that determining mechanism apoptosis initiation. The relation photodynamic effect is described. organized data on molecular mechanisms systems. Singlet due to its high reactivity have damage structural proteins, enzymes nucleic acids resulting different pathologies (diabetes mellitus, cardiovascular diseases, cataract, etc.). On level, "the target" membranes where phospholipid oxidative degradation initiated by role central molecule providing therapy regulation ensemble" active forms. rational use emphasized be base therapy. latter used particular, oncological cardiosurgical pathologies.